Discovery & Development of Tenapanor for the Treatment of Hyperphosphatemia in Patients with CKD on Dialysis: A Novel Blocker of Paracellular Phosphate Absorption

Time: 5:00 pm
day: Day Two


  • Physiology of phosphate homeostasis and the cardiovascular sequelae of hyperphosphatemia in patients with kidney disease
  • New mechanistic understandings of phosphate absorption and control
  • Clinical development of tenapanor as a novel blocker of paracellular phosphate absorption