Primary Kidney Cells for Modelling Chronic Kidney Disease in vitro
Time: 11:30 am
day: Track 1 - Day 2 AM
- Human podocytes maintain high levels of key podocyte markers, including nephrin, podocin, WT1, CD2AP.
- Well-validated Podocyte Toxicity Assay senses injury through barrier integrity (TEER) measures and passage of fluorescently-labelled dextran molecules.
- Disease modelling in podocytes, proximal tubule cells and renal fibroblasts with monitoring of fibrosis readouts – matrix deposition – using high content imaging.