Harnessing the Message of the Extracellular Matrix to Find CKD Disease Endotypes & Inform on Treatment Efficacy

Time: 4:30 pm
day: Conference Day 1


  • Imbalance in the extracellular matrix (ECM) turnover causes kidney fibrosis, which is one of the best prognosticators of kidney failure
  • Non-invasive biomarkers of ECM turnover are associated with an increased risk of outcome in CKD and can identify an endotype of patients with high disease activity that have the potential to respond to treatment
  • Treatments that can alter the dysregulated ECM turnover have the potential to halt disease progression