Pathophysiology of the Transition from AKI to CKD: Mechanisms of Injury & Repair in AKI and CKD Progression
Time: 2:00 pm
day: Day One Track 1 PM
Details:
- Examining the biological overlap between AKI and CKD, emphasizing the role of maladaptive repair, inflammation, and fibrosis in disease progression
- Investigating key drivers of injury, including tubular epithelial cell injury and endothelial dysfunction, and how repair mechanisms, if dysregulated, lead to chronic disease
- How understanding the transition from AKI to CKD can open up novel therapeutic targets for early CKD intervention
- Focus on therapeutic strategies aimed at modulating repair pathways, including the potential role of senescence and autophagy modulators, and anti-fibrotic agents.
