Preclinical RCTs to More Reliably Predict Human RCT Results: Data on Lupus Nephritis & CKD Combination Therapies

Time: 2:30 pm
day: Day 1 Track 1 PM


  • Strategic “go-no-go” decisions involving more reliable ways of animal experimentation to minimize investment failures
  • Insights from a multicentre pRCT on baricitinib in murine SLE/ LN correctly predicting the outcome of two human RCTs
  • Insights from a single centre pRCT on triple RAS/SGLT2/MR blockade in mice with progressive CKD