Preclinical RCTs to More Reliably Predict Human RCT Results: Data on Lupus Nephritis & CKD Combination Therapies
Time: 2:30 pm
day: Day 1 Track 1 PM
Details:
- Strategic “go-no-go” decisions involving more reliable ways of animal experimentation to minimize investment failures
- Insights from a multicentre pRCT on baricitinib in murine SLE/ LN correctly predicting the outcome of two human RCTs
- Insights from a single centre pRCT on triple RAS/SGLT2/MR blockade in mice with progressive CKD