Samvel Gasparyan

Samvel Gasparyan

Company: AstraZeneca

Job title: Statistical Science Director

Seminars:

Mastering Hierarchical Composite Endpoints: Challenges & Opportunities in CKD Trials 1:30 pm

Hierarchical composite endpoints (HCEs) combine multiple clinical and surrogate endpoints in a single trial, providing a pathway to demonstrate efficacy across various outcomes in CKD trials. However, the complexity of developing, ranking, and interpreting HCEs presents unique challenges, especially in CKD trials where surrogate endpoints such as proteinuria or GFR slope play a critical role.…Read more

day: Pre-Conference Workshop C

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