A Patient-Centric approach to CKD Drug Discovery: Integrating Clinical Insights with Human Model Systems
- A patient-centric discovery framework to bridge the translational gap in CKD research
- Leveraging multi-OMICS analyses from large patient cohorts to understand disease mechanisms and identify novel therapeutic targets with high clinical relevance
- Utilizing advanced human model systems to recapitulate CKD molecular states
- An example application of targeting pathogenic mechanisms in the diseased kidney using in vivo systems and tailored in vitro assays