Advancing CKD Clinical Trials via Adaptive Platforms: Novel Endpoints, Basket Strategies & Collaborative Frameworks
- Explore how adaptive platform trials can strengthen nephrology research by creating sustainable infrastructures that support multiple sponsors, consistent site engagement, and faster patient recruitment
- Examine emerging alternatives to traditional eGFR slope endpoints, including hierarchical composites and win ratios, to deliver more clinically meaningful and regulator-acceptable outcomes
- Discuss how umbrella and basket trial designs can integrate CKD and cardiovascular populations to drive efficiencies and shared insights across comorbid conditions
- Consider how collaboration between industry, regulators, and investigators can overcome perceived risks of platform trials, facilitate indication-seeking studies, and enable broader access to patient populations