Introducing Cardiac Kidney Metabolic Syndrome (CKM) – Pathophysiology & Impact on Drug Discovery
Time: 1:30 pm
day: Day One Track 1 PM
Details:
- Discuss the underlying metabolic disturbances that characterize CKM, including mitochondrial dysfunction, inflammation, and the dysregulation of glucose and lipid metabolism, explore how these processes drive CKD progression and impact kidney function
- Explore the added complexity of target ID and validation in CKM
- Investigate metabolic pathways in the pathogenesis of CKM, and how these pathways can facilitate the discovery of more precise molecular targets and guide drug design
- Discuss novel approaches to preclinical modeling of CKM and how better-defined disease models can improve the translation of experimental therapies into clinical settings